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Mitochondrial Diseases, Sjögren's Syndrome And von Hippel-Lindau Disease: Rarities With Anesthetic Implications

Anesthesiology News - Dec 14, 2017
von Hippel-Lindau (vHL) disease, named after Eugene von Hippel (1904) and Arvid Lindau (1927), is an autosomal dominant inherited systemic cancer syndrome that results in cysts and hemangiomas in many organs, especially involving the eye and central ...

PBRM1, VHL Expression Linked With Clear Cell RCC Aggressiveness

Cancer Network - Jan 10, 2018
Reduced expression of PBRM1 (polybromo-1 gene) and VHL (von Hippel-Lindau gene) was correlated with increased tumor aggressiveness in clear cell renal cell carcinoma (RCC), according to the results of a recent study published in Urologic Oncology ...

Peloton Therapeutics Phase 1 Study of PT2385 Published in the Journal of Clinical Oncology Validates HIF-2α ...

Business Wire (press release) - Dec 20, 2017
The von Hippel-Lindau (VHL) tumor suppressor gene is inactivated in the majority of kidney cancer cases, leading to stabilization of HIF-2α and upregulation of the expression of genes that are important to tumor growth and metastasis. While many ...

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Von Hippel Lindau Disease

Overview of Von Hippel Lindau Disease.

Medical Marvels - Von Hippel-Lindau Disease

NewYork-Presbyterian neurosurgeon Michael B Sisti, M.D., and patient Manuel Greco discuss Manuel's case. Manuel has Von Hippel-Lindau disease, a rare condition that causes tumors to grow in...

An Introduction to Von Hippel LIndau disease

A Comcast Newsmaker interview with Jeannie McCoy, board member of the VHL Family Alliance, about her experience and her family's experience with Von Hippel Lindau disease.

Neurofibromatosis, Tuberous Sclerosis & Von Hippel Lindau, Acoustic Neuroma Lisch Nodule NF1 NF2

ERRATA: Less than half of all VHL is caused by a deletion of the VHL gene. There are a number of different mutations to the gene that cause the disorder. Neurocutaneous Syndromes are a group...